Actemra
Actemra, also known as tocilizumab, is a prescription medication used to treat certain autoimmune diseases. It works by targeting and blocking a specific protein in the body called interleukin-6 (IL-6), which plays a key role in inflammation. By doing so, Actemra helps reduce symptoms like swelling, pain, and joint damage.
How Actemra Works
Actemra is a monoclonal antibody that targets and blocks a protein in the body called interleukin-6 (IL-6). When IL-6 is activated, it can cause the immune system to become overactive, leading to inflammation and symptoms of autoimmune diseases. By blocking the IL-6 receptor, Actemra helps regulate the immune system’s activity, reducing inflammation and alleviating the signs and symptoms of these conditions.
What Does Actemra Treat?
- Rheumatoid arthritis
- Giant cell arteritis
- Certain types of juvenile arthritis
- Severe COVID-19 in hospitalized patients
DOSAGE
Common dosage for Actemra varies by condition and administration method:
Rheumatoid Arthritis:
- IV infusion: 4-8 mg/kg every 4 weeks
- Subcutaneous injection: 162 mg every week or every other week
Giant Cell Arteritis:
- Subcutaneous injection: 162 mg every week
COVID-19 (hospitalized patients):
- Single IV infusion: 8 mg/kg (maximum 800 mg)
Juvenile Arthritis:
- Weight < 30kg: 10 mg/kg IV every 4 weeks
- Weight ≥ 30kg: 8 mg/kg IV every 4 weeks
Note: Dosage must be determined by your healthcare provider based on your specific condition, weight, and response to treatment.
Common Side Effects
- Increased risk of infections
- Headache
- Upper respiratory tract infections
- High blood pressure
- Injection site reactions
- Abnormal liver tests
Important Safety Information
Contact your doctor immediately if you experience:
- Signs of infection (fever, chills, persistent cough)
- Stomach pain
- Changes in vision
- Unusual bruising or bleeding
- Yellowing of skin or eyes
Never start or stop Actemra without your doctor’s guidance. Regular blood tests are required to monitor your health while taking this medication.
Before Starting Actemra
Tell your doctor if you:
- Have any current infections
- Are planning to get vaccinated
- Have liver disease
- Are pregnant or planning pregnancy
- Have a history of stomach ulcers
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